Endocrine Abstracts

Background: In Hashimoto’s thyroiditis, chronic inflammation and autoimmunity increases oxidant radicals and cause oxidative stress. However, the effect of levothyroxine therapy on the oxidant and antioxidant systems is not known in overt hypothyroidism. Therefore, we sought to investigate the effect of levothyroxine sodium therapy on oxidative stress in patients with Hashimoto thyroiditis and overt hypothyroidism.Materials and methods: 36 patients ...